In some cases, antibiotics are included in the treatment regimen for prostatitis. The choice of a particular drug depends on a number of factors. Antibacterial therapy of acute and chronic forms of the disease has a number of significant differences.
Taking antibiotics is an important component of successful treatment of acute and chronic prostatitis. The success of treatment largely depends on the correct selection of the drug and the scheme of its administration.
Indications for the appointment and the effect of antibiotics for prostatitis.
Antibiotics are prescribed when it becomes clear that the inflammation of the prostate is caused by an infection. This applies not only to the acute course of the disease, when pronounced symptoms are forced to provide emergency assistance. Chronic bacterial prostatitis, which presents with a mild clinical picture or without any symptoms, also requires antibiotic therapy.
The indication to take antibiotics is not some specific symptom, but laboratory data indicating the presence of an infection.
To do this, it uses PCR (polymerase chain reaction method), which makes it possible to identify with great precision infections transmitted through sexual contact, as well as the study of urine and prostate secretion, which makes it possible to detect the presence of bacteria.
Sometimes the infectious inflammation is hidden; in this case, the level of leukocytes in the secretion of the gland does not exceed normal levels. To determine if there is an infection, the doctor prescribes a test dose of an antibiotic. After a week of taking this drug, the analysis is taken again, and if the level of leukocytes is above 25 units, then we are talking about a hidden course of an infectious lesion of the prostate. In this case, antibiotics become mandatory.
The choice of antibiotic to treat inflammation of the prostate depends on several factors. The key is which bacteria have been identified and which drugs they are sensitive to. There is no universal cure.
The principle of action of antibiotics depends on the type of drug used, the form of the disease and the agents causing inflammation. However, the general essence can be reduced to several stages:
- The penetration of drugs into the blood by assimilation through the gastrointestinal tract or by intravenous administration.
- The penetration of active substances into the tissues of the prostate gland and the destruction of the causative agent of the disease.
- The effect of accumulation in the tissues of the gland, allowing it to continuously fight infection.
The last step is particularly important, as some antibiotics are only bacteriostatic. This means that they only affect dividing cells. At the same time, those cells that are in an anaerobic state go unnoticed by them. If the active substance of the drug does not accumulate in the tissues of the prostate, the bacteria that have left the anaerobic state will quickly nullify the entire effect of the treatment.
There are bacteria that are highly resistant to drugs. These are perhaps the most common causative agents of prostatitis, for example, Escherichia coli. They build hard capsules and biofilms that reduce the effects of active drug ingredients. In this case, it is necessary that the drugs have the ability to destroy the protective layers of these bacteria. It is also important to take the medication until the end, even when the symptoms of the disease have already disappeared.
Groups of antibacterial agents for the treatment of prostatitis.
There are several groups of antibiotics that are effective (alone or in combination) against the bacteria that cause inflammation of the prostate gland. The choice of a specific group of drugs depends on a number of factors: "weak points" in the identified bacteria, the patient's comorbidities, the severity of the course of prostatitis, its form, and the side effects of the drug.
The main groups of antibacterial drugs for prostatitis include:
Antibiotics in this group have a bacteriostatic effect, which means that they prevent cell division, growth and development.
Do not think that bacteriostatic drugs are unambiguously ineffective. This effect is sufficient to eliminate the infection, as long as the patient does not have impaired immunity.
Such drugs disrupt the connection between RNA (which "gives orders" for the growth and division of pathogens) and the ribosome (which carries out these "orders"), thus suppressing the production of proteins, the building material for new cells.
Medicines of this group are effective in the fight against the following pathogens:
Drugs from this group are prescribed selectively due to the large list of side effects.
Preparations of this group also have a bacteriostatic effect that affects dividing bacteria. However, they have a different principle of action - they stop the production of the main component of the bacterial cell wall - peptidoglycan.
Since there are many bacteria that have developed resistance to antibiotics in this group, a subgroup of protected penicillins has been developed.
These antibiotics are effective in treating inflammation caused by the following bacteria:
Drugs in this group are prescribed with care due to the high risk of allergic reactions. To treat inflammation of the prostate, drugs based on oxacillin, ampicillin and amoxicillin are prescribed.
These are powerful bactericidal drugs that not only prevent cell division, but also destroy them. This occurs in two steps: interruption of peptidoglycan production (cell wall destruction) and enzyme release.
Drugs of this group are effective against:
- Proteus bacteria;
Drugs in this group include drugs based on ceftriaxone, cefilin, cefpiron and others.
The group of the safest antibiotics that cause the fewest side effects. The principle of its action is the cessation of the production of proteins for cell construction. What will be the effect (bactericidal or bacteriostatic) depends on the choice of drug and its concentration in the body.
Antibiotics of this group are effective against the following bacteria:
Not all doctors prescribe drugs in this group for the treatment of prostatitis because, although it is logical to assume their effect, limited studies have not been conducted on this topic. Drugs in this group include drugs based on azithromycin and clarithromycin.
These are not antibiotics in their classical sense, because antibiotics are naturally occurring drugs or their closest synthetic counterparts. Fluoroquinolones have no analogues in nature.
Drugs from this particular group are most often prescribed by urologists. And there are good reasons for it:
- First of all, they have a very wide spectrum of bactericidal action, not inferior to natural antibiotics with fewer side effects.
- Secondly, they have a very active antimicrobial effect: they affect both the production of DNA, preventing its copying, as well as topoisomerase (an important part of the integration of the virus in cells), and RNA, and cell walls. cell membranes and other processes. that ensure vital activity and the process of cell division - such a massive attack from all fronts has good results.
Fluoroquinolones are effective against:
- intestinal and Pseudomonas aeruginosa;
- chlamydia and other bacteria.
Antibiotics of this group are used for the complex treatment of Koch's bacillus. Therefore, before starting these drugs, it is important to make sure that there are no tuberculosis-causing agents in the body. The fact is that a separate intake of fluoroquinolones helps Koch bars to develop resistance to other antibiotics, and the process of treating tuberculosis becomes much more complicated.
The most effective antibiotics for inflammation of the prostate
Even the most effective antibiotic will be useless and even harmful if the reason for choosing this drug is advertising, the opinion of incompetent people that this remedy helped, or the fact that this drug was effective last time. There is no drug that is active against all bacteria and viruses, but each group of antibiotics has its best representatives.
General principles and features of antibiotic therapy for acute and chronic prostatitis.
The treatment regimen and the choice of drugs depends on the form of prostatitis. There are similarities and differences in the treatment of acute and chronic prostatitis.
For the treatment with antibiotic therapy of any type of prostatitis, the following aspects are characteristic:
- it is mandatory to contact a doctor and pass tests to identify the pathogen;
- treatment should be continued according to schedule, even when complete recovery appears to have occurred.
At the same time, when choosing drugs for the treatment of inflammation, you need to take into account a few different factors. Therefore, for the treatment of chronic prostatitis, the ability of the active ingredients to penetrate the cells of the prostate is of fundamental importance. It has been shown that a high concentration of the drug in the blood is not enough. Not all broad-spectrum drugs, even the latest generation, have such capabilities. The situation is different when it comes to acute inflammation: the permeability of prostate cells for the entry of drugs from the blood increases.
The ability of drugs to penetrate and accumulate in tissues is of paramount importance in chronic inflammation, but less so in acute inflammation.
The second difference is that the acute phase must be treated as quickly as possible, given the severity of the condition. Therefore, preference is given to bactericidal drugs (fluoroquinolones), rather than bacteriostatic ones. In cases where the principle of action of the drug is dose-dependent, the concentration of the drug in the blood and prostate must be sufficient to maintain the bactericidal effect; this applies to drugs from the group of macrolides.
Bacteriostatic antibiotics are selected for the treatment of chronic inflammation and bactericidal antibiotics for acute inflammation.
Natural antibiotics: effectiveness and methods of application.
Considering that almost all antibiotics are of natural origin (or are the closest analogs), it is logical to assume that herbs have a similar effect with better tolerance and fewer side effects.
However, if the action of herbs were sufficient, there would be no need to produce medicines. Therefore, herbal therapy with antibacterial properties is only suitable as an adjunctive treatment or preventive measure for chronic inflammation of the prostate gland.
There are several herbs that can fight bacteria:
- yarrow (can have a bactericidal and bacteriostatic effect on E. coli and enterobacteria);
- bitter wormwood (effective against Escherichia and Pseudomonas aeruginosa);
- eleutherococcus (combats white staphylococcus aureus, E. coli and enterobacteria);
- large banana (fights white staphylococcus, enterobacteria, has a bacteriostatic effect on proteus, has an analgesic effect).
There are many recipes with which you can prepare an antibacterial drug to relieve inflammation. Of herbs, it is better to prepare infusions that do not need long exposure to temperature.
For almost any herb, the following recipe is suitable:
- For one part of the herb, take ten parts of water at room temperature.
- Heat the mixture for a quarter of an hour in a boiling water bath.
- Infuse for 45 minutes.
- Pass through a filter, such as gauze.
The infusions are more effective if they are taken immediately after their preparation.
In addition, hazel bark, aspen and chestnut skin are used to combat prostatitis. From such material it is better to prepare decoctions. Each plant has its own recipe, but in general terms, the preparation of a decoction is as follows:
- Wash and grind the raw materials.
- Put in water so that it completely covers the branches or bark.
- Boil in a water bath for half an hour.
- Let cool for 10 minutes and drain the broth, squeezing the raw material.
Broths can be taken within 2 days from the moment of preparation.
The effectiveness of treatment depends on several factors: the choice of the desired natural antibiotic, the acquisition of high-quality raw materials (it is better to prepare it yourself), and the correct preparation of the infusion or decoction.
Antibiotics for prostatitis are selected depending on the infection that caused the inflammation, the form of the disease and the general state of health of the patient. Each drug has contraindications and side effects, so a urologist should be consulted before taking it. The same applies to medicinal herbs with antibacterial effect.